Haemodynamic effects of diltiazem in healthy volunteers [letter]
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چکیده
منابع مشابه
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متن کاملEffect of the CYP3A inhibitors, diltiazem and ketoconazole, on ticagrelor pharmacokinetics in healthy volunteers
OBJECTIVES Two open-label, two-period, crossover studies in healthy volunteers were designed to determine the pharmacokinetic interactions between ticagrelor, a P2Y12 receptor antagonist, and a moderate (diltiazem) and a strong (ketoconazole) cytochrome P450 (CYP) 3A inhibitor. METHODS Seventeen volunteers received diltiazem (240 mg once daily) for 14 days. In the second study, ketoconazole (...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1980
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1980.tb00522.x